Why not all obese people are diabetic

Why not all obese people are diabetic

There are a lot of people who are fat and obese and eat too much fat and sugar while engaging in limited exercises or walking but are not diabetic or don’t develop Type-2 Diabetes. Why? It is because their gut bacteria play a role in it.

Andrey Morgun and Natalia Shulzhenko of Oregon State University and Giorgio Trinchieri of the National Cancer Institute have found that a particular type of gut microbe leads to white adipose tissue containing macrophage cells, large cells that are part of the immune system, associated with insulin resistance. Their findings have been published in the Journal of Experimental Medicine.

"Our experiments and analysis predict that a high-fat/high-sugar diet primarily acts in white adipose tissue (in the human body, white adipose tissue is the main type of fat) by driving microbiota-related damage to the energy synthesis process, leading to systemic insulin resistance," said Morgun, associate professor of pharmaceutical sciences in the OSU College of Pharmacy.

"The so-called 'western diet', high in saturated fats and refined sugars, is one of the primary factors. But gut bacteria have an important role to play in mediating the effects of diet," Shulzhenko said.

Diabetes is a chronic (long-lasting) health condition that affects how your body turns food into energy. Most of the food you eat is broken down into sugar (also called glucose) and released into your bloodstream. When your blood sugar goes up, it signals your pancreas to release insulin.

If you have diabetes, your body either doesn’t make enough insulin or can’t use the insulin it makes as well as it should. When there isn’t enough insulin or cells stop responding to insulin, too much blood sugar stays in your bloodstream. Over time, that can cause serious health problems, such as heart disease, vision loss, and kidney disease.



Leave a comment