New Delhi, Oct 28: A team of researchers has identified the brain cells that
trigger hedonic eating, a development that could provide a basis for new
poor dietary choices and maladaptive eating behavior such as hedonic eating –
eating when not hungry – and the lack of physical activity result in obesity.
a recent study, that was published in Nature Neuroscience and reported
by Medical News Today, scientists discovered that a group of neurons in
the amygdala, a part of the brain involved in experiencing emotions and
decision-making, may also trigger hedonic eating.
identification of the neuronal substrates mediating overeating could provide
new molecular targets for devising new anti-obesity treatments,” said
Alessandro Furlan, Assistant Professor at the Department of Neuroscience at
Karolinska Institutet, Sweden, and one of the study authors.
part of the study, the researchers conducted several experiments on mice when
they observed the neuronal behavior of the rodents in response to eating
regular chow and also a high-fat diet (HFD) after food restriction.
an HFD, but not chow, the researchers noticed higher activity levels among
certain neurons in a part of the amygdala known as the interstitial nucleus of
the posterior limb of the anterior commissure (IPAC).
findings indicated that certain neurons of the IPAC may be activated following
the consumption of palatable food. Further demonstrations revealed that these
IPAC neurons could also be activated in the presence of fatty and sugary food
and smell in the absence of hunger.